PharmaGABA features a natural source of the inhibitory neurotransmitter – GABA. GABA supports restful sleep, helps act like a ""brake"" on stress, and helps provide a focused state of mind.* Gamma-aminobutyric acid (GABA) is a major calming brain chemical or neurotransmitter.* Clinical studies show that the natural form of GABA that is in Thorne's PharmaGABA can help decrease the brain's stress-related beta waves and help increase the production of its alpha-waves, creating a sense of physical relaxation while maintaining mental focus.* Other studies have shown reduced pupil diameter, heart rate, and two natural biomarkers of stress – salivary cortisol and chromogranin A – all signs of relaxation.* In addition, studies also indicate GABA can support sleep.*In a head-to-head, double-blind trial of natural PharmaGABA versus synthetic GABA, the synthetic GABA did not demonstrate these supportive effects.* PharmaGABA-250 offers 250 mg of natural GABA per capsule, while PharmaGABA-100 offers 100 mg per capsule. Both are non-habit forming. • Sleep* • Sports Performance* • Stress* **